![]() ![]() The mean platelet volume measures the size of the platelet. ![]() The mean platelet volume test is one of the parameters checked in a routine blood test. Bone marrow hypoplasia ( a disease caused by a decreased production of blood cells).Exposure to some type of drugs that could harm the cells (cytotoxic medication) usually drugs used for chemotherapy.Inflammatory bowel disease such as ulcerative colitis and Crohn’s disease.With the interpretation of other blood level parameters, a low mean platelet volume could indicate the following: They are old platelets, which means that the bone marrow has trouble producing new platelets. (6, 7, 8, and 9) MPV blood test lowĪn abnormally low mean platelet volume means that y our platelets are smaller than the average. Other possible conditions caused by a high mean platelet volume are heart-related disease, hyperthyroidism, diabetes, high blood pressure, vitamin D deficiency, diabetes, atrial fibrillation, stroke, and preeclampsia. It signals a reduced survival rate, especially in patients with lung cancer, colon cancer, ovarian cancer, cancer of the stomach and kidneys, pancreatic cancer, endometrial cancer, and breast cancer. On the other hand, if you have cancer and your mean platelet volume is high, it means that the cancer cells have already metastasized or spread to other body parts. If you have a family history of cancer or exhibiting signs and symptoms of cancer (abnormal changes in the breast, skin abnormalities, an abnormal lump under the skin, change in bowel habit, feeling weak, night sweat, unusual bleeding, and abnormal changes in bowel habit) your doctor might need to perform additional test to confirm the diagnosis. (4, 6) A high MPV can be linked with the following:Ī high MPV is linked with platelet activation as a result of an encounter of platelets to tumor by-products. However, if your MPV is high and your platelet count is low, it could indicate a possible bone marrow disorder (rapidly producing platelets) leading to the destruction of the older platelets. If the mean platelet volume is high, it means that your platelet is higher than the average, which means that you are producing too many platelets. High MPV/normal platelet count – It occurs in people with chronic myelogenous leukemia (cancer) and hyperthyroidism. ![]()
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